Why should anyone opt for a personal loan?

When you are in dire need of cash, a personal loan can be your saviour. Most of the personal loans are unsecured, which does not require you to pledge your assets like property, home, gold, etc.

The best possible way to get a personal loan in Bangalore is by applying with NBFCs (Non-Banking Financial Companies) as they quickly approve and instantly disburse your loan amount into your account in a few hours. Moving ahead, let us discuss the features and benefits of availing a personal loan in Bangalore.

Instant to approve – You can now apply for a personal loan in Bangalore, right from the comfort of your home. Because the application process is paperless and completely carried out online. If you can qualify for the eligibility criterion set by your lender and complete all the other formalities, your loan application will be approved instantly. Based on the lender you have chosen the loan amount will be disbursed within a few hours to a few days into your account.
Minimal paperwork – Just by submitting only a few mandatory documents concerning your identity, residence, and income as proofs, you will be approved with a personal loan in Bangalore. The loan application process is fully digital and there are no additional documents taken from you.
Flexible to repay – Because of the increase in demand for personal loans in Bangalore, many lenders are offering loans under relaxed guidelines. You have the advantage of choosing a tenure which suits your needs. So, you can pay the loan amount as per your convenience and with extreme financial ease.
Transparency – It is advisable to choose a lender who offers loans with no hidden charges and under complete transparency. So you can avail the loan after knowing all the terms and conditions beforehand.
Eligibility for a personal loan

The eligibility criterion slightly differs from one lender to another. To qualify for a personal loan in Bangalore, the most common eligibility criteria followed:

You must be more than 21 years of age
Must be of Indian nationality and
Should earn a good source of income
Documents that are to be submitted for a personal loan

The basic documents requested by your lender while approving your loan is:

Identity proof – Aadhar/Driving license/Passport etc.,
PAN card
Address proof – Driving license/Utility bills/Aadhar etc.
Last 3 months payslips
Photo or a selfie
Conclusion

Because of Bangalore’s lifestyle and cost of living, many individuals may face financial troubles. To balance yourself financially, it is always advisable to opt for a personal loan in Bangalore. Check out for one of the best lenders like FlexSalary. They provide loans throughout India, and you can get instant access to money if you have a cash crunch.

Global stock markets: Dow 30, -0.6%; S&P 500, -0.8%; Nasdaq, -1.3%; Nikkei, -0.3%; Hang Seng, +0.1%; KOSPI, +0.5%

Last week, Nifty started on a negative note, fell more than 2.2%. However, it found support at its 21-DMA on Monday. In the next four sessions, the volume of shares traded dried up relatively. On Friday, it succumbed to selling pressure, taking cues from global markets. Selling was seen across the sectors, with Maruti Suzuki India (+1.7%) being the only advancer for the day. Friday’s action qualified as a distribution day as the fall was more than 0.2% on volume higher than the previous session. During the last week, the index added two distribution days (Monday and Friday). However, the distribution day registered on July 30 expired on Thursday. Overall, it has five distribution days.

During the week, all the sectoral indices closed lower, led by Nifty PSU Bank (-8.9%) and other financial related sectors. Realty (-5.5%) and Energy (-3.4%) also succumbed to selling pressure.

The market status was recently changed to an Uptrend Under Pressure. We will be slightly cautious while initiating fresh long positions. We will change the status to a Downtrend if two or three more distribution days are added or if Nifty breaches its 50- and 200-DMA. On the flip side, the status will be shifted back to a Confirmed Uptrend if Nifty retakes the 11,795 level (high made during the recent rally).

Key News

Info Edge (India) (Nse), General Insurance Corp Of India and R P P Infra Projects will report their Q1 FY21 results today.

Repco Home Fin. reported Q1 FY21 results yesterday. Revenue from operations was up 2.9% y/y to Rs 337.71 crore. It reported a profit of Rs 69.50 crore, compared with a profit of Rs 67.4 crore for the same quarter last year.

National Aluminium (Nse) reported Q1 FY21 results yesterday. Revenue from operations was down 33.8% y/y to Rs 1,380.6 crore. It reported a profit of Rs 16.7 crore, compared with a profit of Rs 98 crore for the same quarter last year.

O’Neil Market Condition Report

For the 24 emerging markets tracked by our institutional research team, the market status breakdown is as follows: Confirmed Uptrend, 54%; Rally Attempt, 8%; Uptrend Under Pressure, 30%; Downtrend, 8%.

For the 24 developed markets tracked by our institutional research team, the market status breakdown is as follows: Confirmed Uptrend, 17%; Rally Attempt, 0%; Uptrend Under Pressure, 70%; Downtrend, 13%.

Buy Watchlist:

Bharti Airtel, Biocon (Nse), Balkrishna Industries, Sun Pharm.Industries, Multi Cmod.Ex.Of India, Indian Energy Exchange, Infosys, Tata Consultancy Svs., Escorts, and Aurobindo Pharma

The advent of smartphones and the internet has revolutionized communication among us. First, we communicate via phone calls, then shifted to SMS. And, now we all moved to WhatsApp. WhatsApp is a popular messenger app that provides an instant messaging facility.

People are moving away from calls to text messages. Reasons are

Text is more convenient than the call. They can check the messages on their own time
Texts are less disruptive than the phone calls
Privacy: Texting is a private communication channel
Texting convenient than the Calls where the atmosphere is noisy
For Multitasking
Less stressful because it does not require immediate attention, we can respond at our convenient time.

When coming to texting, WhatsApp is quite popular in the world. Today, active WhatsApp user is more than 1 billion, which means it reached every corner of the world.

What makes WhatsApp famous among millennials?

It is free to send/receive messages
We can send multiple images, files, documents, locations & contacts
We can easily see the person to whom send message received & also, seen or not
Easily set profile picture & update bio
Get an idea about, to whom we communicate, is online OR last active hours

In SMS, it cost us to send messages. We can’t send images, documents, files through SMS. Also, it does not show the person to whom we message has seen the text. We can not update bio & profile photos. Because of these reasons, SMS has losing its popularity.

Why SMS Marketing is Not Effective Nowadays?

When SMS was a common mode of communication among users, businesses use this platform to send their offers and discount on their products & services to their customers. Now, people consider this as a spammer, do not open the messages unless it is more relevant.

For start-ups & small businesses, SMS Marketing is a waste of their precious time, money, and energy because almost no one bothers to open a message to read, they just swipe away & delete it. Also, it has a character limit & not equip to send visuals. In this era, millennials prefer visuals to text. Customers do not prefer to solve their queries by SMS.

WhatsApp Marketing For Businesses

WhatsApp is a mobile app that enables us to send messages to anyone in the world for free. It cost us nothing to send messages, images, and documents. It offers us many ways (images, audio, videos, documents, files, etc.) to communicate with consumers.

WhatsApp Vs SMS Marketing

WhatsApp has end-to-end encryption which makes it very secure.
It cost us to send SMS, on the other hand, WhatsApp is free
We create groups on WhatsApp to send product updates, but in SMS it is not possible
In SMS, it has a text limit and can’t have the functionality to send images, video, documents, etc.
Open Rate in SMS – 98%, whereas in WhatsApp – 99%

People are, nowadays, ignore SMS mostly but hardly ignore WhatsApp messages. For businesses, it is important to find a platform that has a high customer base and better ROI. Businesses can easily save up to 50% on marketing costs using WhatsApp & increase 50% their ROI.

However, manage to have a handy list of customer contacts is no more difficult, separate out contacts that using WhatsApp is quite hard. You check manually and send messages each one by one, but it cost your time & energy.

Here is the one app, Export Contacts For WhatsApp, that quickly filters out contacts that using WhatsApp into a single file. Also, we can chat with our customers without saving their number & send bulk messages to contacts. The Application works on Mobiles as well as Windows Desktop. Unlimited Contacts can be exported at a time.

It is easy to use this app.

º Launch the Application

º Click on Export Contacts

º A Pop-up Window will generate asking you to Enter the file name

º Enter the file name as per your requirement and Click Export

º Successful Message and Location of Exported File Will be displayed

(Exported file is directly stored in the Mobile for usage)

For texting, Whatsapp has become more famous. It is a very flexible tool and has features to create groups, send images, videos, documents, locations. These reasons make WhatsApp marketing more effective than SMS Marketing.

What are cockroach startups
Comparing startups with cockroaches is also a very interesting subject.

Cockroach survives even in nuclear war, so today investor is also searching for such startups, which even if they do not get next level investment, at least business will continue.

Every startup dreams of becoming a unicorn, in his thoughts the business strategy is also according to the unicorn.

Every startups should also plan while making a business plan that if it does not get funding and if it is delayed in getting funding, then how will the business it is planning be completed?

Will the team he is carrying with him, if funding is not received or is late, how will he pay their salary and how will the operational expenses be met.

Every startups think that their idea is the most unique and fundable idea, but sorry, it does not happen.

Don’t know how many ideas are born everyday but only a few ideas reach the next level.

Startups Mindset
Today, the biggest reason why investors want to invest in cockroach startups is their mindset.

The startup does all the planning on the basis of the idea, makes a business plan, prepares the presentation and works with a very positive mindset and convinces his heart and mind that what he is going to do is exclusive and as soon as he presents Investors will shower money on him.

But he does not want to think that what will happen if the project is not funded.

He does not have the answer to this because if someone asks him about this, he will think that he is thinking negatively.

Rather, thinking about the negative aspect and finding its solution in advance will be considered as a positive approach.

So I request all those startups to think about every aspect of the business and then jump into the field of funding.

Whether the money is yours or that of the investor, give value to it and invest in the right direction. Today we see in daily news that he got funding, he got funding, someone is raising rounds for marketing and someone is raising for capacity increase, the condition of some is that their loss value is more than sale value, that they spend 750 to get a sale of 500 with the thought that the customer will become theirs. It is their thinking that they will change the shopping behavior of the customer but in most of the cases startups fail to do so and in the end who is the investor.

Sustainable unit economics is key
As we have already discussed, the business should be self-sustainable, money is needed to grow any business, if funding is not available, then at least it will continue.

As we saw in covid time, it started raining for edtech startups and they were also getting funding.

See the difference of thinking here, did the startups think that the lockdown that happened in covid will continue forever and the investor’s thinking also matters here whether the lockdown will never open.

One of their thoughts may also be that a person has never been locked at home for so long and now his behavior will change, if the behavior does not change then the business will be sustained. But human nature does not like to be locked up, what was its impact, startups which started thinking of covid in covid time are either closed today, or are waiting for a merger or someone acquired and bought them and are sitting in this wait…READ MORE….

The whole objective of organizing dome projection, in any event, is to present a more influential and engaging experience for the viewers by visual stimulation. The immersive technology generates a 360-degree visual reality onto the spherical overhead of the dome supported by the software-based projection incorporated with light and sound while offering the viewers an immersive experience at a hemispherical angle without having to wear any special spectacle.

During the last couple of years, this innovative idea has grasped the attention of various brands to employ it as a highly effective promotional tool. Aside from the marketers and businesses the potential of the immersive technology to generate infinite creative opportunities has made it increasingly popular for other events and industries including education, healthcare, corporate training, medical conference as well as social events like concert parties, wedding ceremonies, etc.

Contextually, it’s worth mentioning, that the success of your dome projection event, irrespective of it is intended to promote a new brand, medical seminar, workforce training, or wedding celebration party, depends immensely on the depth of technological understanding, experience, expertise, specialization of the content production team that you are likely to work with. Therefore, when completing projection into a dome to make your forthcoming event credible, engaging, and memorable to your audience or guests, ensure that you are joining hands with a real professional with a highly successful track record in the industry.

However, finding the right crew could seem challenging for you in the mass of service providers in the industry. The article suggests you follow five practical steps to reach the most desired professionals faultlessly and productively.

1. Complete Your Homework

Homework with due diligence is your foremost step to go ahead. You need to consider three factors including

• The objective of your event/ theme;

• How much are you need (based on the volume of your invitees and program details)

• Consider your budget.

First of all, make sure on the above factors which will come in handy to make realistic research and accordingly hire the right community capable to meet your objective and event t deliverables within your budget.

2. Research Well

Although depending on referrals from your friends, associates and other like-minded professionals can be a helpful source, however, since not all dome projection programs are of equivalent types, depending on the complexity and extent of your event, make sure to research through the internet for a specialized dome projection team.

3. Know the Background

Knowing the background of a service provider in the domain should be your priority concern. As you browse the website, check what they do, their background, specialty area, key members, and the standard of clients they have worked with. Remember, that status of clientele is a major emblem that tells the value of the group.

4. Type of Domes/ Services

Whether you should go for a geodesic dome or an inflatable one for your dome projection should be decided based on the type and volume of space you need, the number of guests or participants, your funding, etc. Both are equally popular while inflatable domes are gaining faster demand due to their many advantages.

So, accordingly, check whether it’s equipped with complete dome solutions while you need to verify the size of domes, their capacity, installation time, etc. Typically, due to the structural complexity and multifaceted activities for setting up, geostatic domes take a longer time nearly 2 weeks while installation of inflatable can be done even within a few hours. Make sure that the company is capable to provide a complete range of solutions having expertise in

• Dome designing and developing,

• Dome projection,

• Content development,

• 360 projection mapping,

• Interactive program designing, and

• Consultancy

5. Project Portfolio

Although we have placed this topic at the last step, you can consider it as the first step as well. Because when it comes to dome projection, the project portfolio that it has performed is the most crucial decisive factor for you. Spend enough time to study the different types of dome projection works that it has handled earlier. The richness of the projects, the clients for whom they are being designed, what are the comments, etc. Thorough research of the portfolio, section will give you a great insight into the creativity level, recognition, and success story of the team.

Children are often at risk of getting tangled up in cords while playing around a window. Cordless blinds in Sydney come in many different types, such as pleated shades that drape across the top but do not touch or pull on any cords to open them. They can be mounted inside or outside windows and have no hanging cords near children’s reach level for added safety.

Some blinds and shutters in Sydney come with motorized operation, making it much safer and easier to open and close your window treatments. You can also find motorized shutters, that are made of vinyl, aluminium or wood. These styles come with both inside and outside mounting options to suit your home’s needs. Motorized window treatments offer the ultimate child protection because they will close themselves without any cords for a hands-free closure system.

It’s important to maintain your cordless or motorized window treatments with regular cleaning. For help, consult the manufacturer instructions that came with your product. If you have a problem and can’t find the answer in their documentation, call customer service for help, because it is always best to follow the right guidelines given by the manufacturer rather than doing something on your own that may damage the window treatment.

Which types of window treatments can be motorised?

Motorised window treatments are a great option for homes with children. With this type of treatment, you don’t have to worry about cords or other items that could potentially be dangerous if they’re pulled on by little fingers.

Some options of window treatment types available in motorized option are:

Roller Blinds – The classic and cost-effective roller blinds in Sydney are a very popular choice among home owners with young families. They are very easy to operate and install and are one of the most low-cost blinds around.
Honeycomb Blinds – A more expensive type of blinds but one that provides greater effects in terms of insulation and noise cancelling. These blinds have air pockets (or cells0 which trap air within them creating an insulative barrier between the window and the room. So, they are ideal for the hot summer months as well as the cold winter months.
Roman Blinds – Roman Blinds in Sydney are also very popular, because they add a lot of style and elegance to a room. Made of fabric, you can select it in different types of fabric, textures and colours to suit your specific needs.
Vertical Blinds – These are a low cost, easy to maintain type of blind. Ideally suited for home offices.
Panel Glides – Panel Glides offer great design aesthetics and style for the room, as well as space saving properties. These panels move along a track and stack up at the end when fully open. They can be made in solid colour or even prints, depending on your style ethos.

Almost all of these window treatment options provide great privacy and light control, offer stylish designs and some are even helpful in providing your home with the best possible insulation and noise cancelling properties. They are ideal for homes with little children, not only because they can be motorized for their safety, eliminating choking hazards that are apparent with cords and chains, but are also great for their rooms, to ensure that only the required amount of light seeps in, helping them to sleep better (we all know how difficult it is to get kids to sleep, right?).

As a parent, you know that your children’s safety is the most important thing. Windows are an area of concern for many parents because they provide easy access to the outside world and can be dangerous if not properly secured. With cordless window treatments you have all the benefits of traditional blinds or shutters without any cords or chains dangling around near potentially hazardous areas in your home.

If you are looking for the best options in terms of blinds and shutters in Sydney which are suitable for homes with children, speak to your local supplier and get their advice. They will be able to better help you with selecting the absolute best. They will also have a wide selection of materials, colours and styles available, so you won’t have to compromise on aesthetics.

Understanding Sole Proprietorship Firm Registration
A sole proprietorship is the most uncomplicated business form, where a single individual owns, manages, and controls the business. This type of firm can operate under any name, provided it doesn’t infringe on existing trademarks. One of the key features of a sole proprietorship is that it’s not recognized as a separate legal entity from its owner, meaning the proprietor is personally liable for all business activities.

Key Characteristics of a Sole Proprietorship:
Single Ownership: The proprietor is the sole decision-maker and beneficiary of all profits.
Tax Benefits: If the firm’s income is below ₹2.5 lakhs annually, it’s exempt from income tax.
Ease of Banking: Registration primarily serves to facilitate banking operations under the business name.
Personal Liability: The proprietor is responsible for all transactions and liabilities incurred by the business.
Registration Modalities for Sole Proprietorship Firms
In India, there are several ways to register a sole proprietorship, each catering to different business needs:

MSME/Udyam Registration: This is beneficial for micro, small, and medium enterprises seeking government benefits.
GST Registration: Mandatory for businesses exceeding the ₹20 lakh turnover threshold or engaging in inter-state trade.
FSSAI Registration: Required for businesses involved in food production or handling.
Shop and Establishment Act License: Necessary for all business establishments, including shops and commercial premises.
Trade License: Issued by the local municipality, it’s essential for certain types of businesses.
Each registration type has its own set of requirements and benefits, and choosing the right one depends on the specific needs of the business.

Advantages of Choosing a Sole Proprietorship
The sole proprietorship model is highly attractive for individual entrepreneurs due to several compelling benefits:

Full Profit Retention: The proprietor enjoys all the earnings without sharing.
Quick Setup: Registration is faster and simpler compared to other business structures.
Individual Tax Rates: The firm is taxed at the individual income tax rates of the proprietor.
Low Costs: The cost of registering a sole proprietorship is relatively low.
Autonomous Decision-Making: The proprietor can make swift decisions without the need for consensus.
Lifetime Certification: Certain registrations like MSME/Udyam or GST do not require renewal.
For more information on how to register your sole proprietorship firm in India, visit Registration Shops, or reach out via email at [email protected].

Additional Considerations
While the benefits are significant, potential proprietors should also be aware of the drawbacks, such as unlimited personal liability and the difficulty in raising capital. Moreover, the lack of a separate legal identity means that the business ceases to exist upon the proprietor’s demise.

Statistical Insights
According to the Economic Survey of India 2021-22, the MSME sector, where many sole proprietorships operate, contributes around 30% to the GDP and 45% to the overall exports from India. This highlights the critical role of sole proprietorships in the Indian economy.

In conclusion, sole proprietorship firm registration in India offers a streamlined avenue for entrepreneurs to launch their ventures. With its ease of setup, tax benefits, and operational simplicity, it remains a popular choice for many business owners. However, it’s essential to weigh the pros and cons and choose the right type of registration to ensure compliance and maximize the benefits.

- Plumbing and heating hi vis workwear

People who work for plumbing and heating related jobs will have to spend a considerable amount of time kneeling down. Due to the same reason, it is important for their attire to be made out of thicker materials. However, the thick material should not restrict their movement as well.

In general, the work attire includes work boots, which are made out of thicker materials. They come along with a steel toe cap, which provides added protection and safety. They can wear shorts or trousers. Even though these look pretty much similar to ordinary trousers, they come along with thick fibres. Moreover, they have multiple pockets, which allows people to get their work done without a challenge. There are padded knees available with workwear, which allows them to ensure the protection of joints, while staying away from injuries.

Plumbing or heating professionals can either wear hi vis t-shirts or jackets with custom embroidery. However, they should provide both comfort and mobility. Moreover, they should come along with safety equipment, such as knee protectors, goggles, respirators, and high visibility jackets.

- Electrician workwear

Electricians have to deal with the risk of electricity at work. On top of that, they have to deal with flame and heat as well (FR Workwear). Hence, their workwear should be in a position to provide protection accordingly. The material for electrician workwear are heat resistant and flame resistant. On the other hand, they have a higher ATPV rating, which is above four. The right amount of heat that could be blocked by the material is indicated by HAF material rating.

Electricians are also wearing insulated rubber gloves as a part of their workwear. Moreover, they are wearing flame protectors for the eyes and necks. Boots are providing the level of safety that electricians want to keep their feet safe. It is essential for all electricians to adhere to this workwear, while they are at work, so that they can overcome injuries.

- Construction workers hi vis workwear

Construction workers can think about wearing hi vis long-sleeved shirts as well as short-sleeved shirts. Moreover, they can wear long pants and work boots. However, the long pants they wear should not contain any tears or rips. On the other hand, work boots worn by construction workers should offer slip and toe protection as well.

Construction workwear come along with a large number of pockets. These pockets are allowing the construction workers to keep their tools along with them at work. Moreover, construction workwear come along with heavy-duty cargo or canvas. Or else, you can find cotton shirts and duck cotton pants, which provide utmost durability and comfort. Similarly, even the jackets worn by construction site workers come along with duck cotton construction, which provides durability and toughness needed.

Apart from workwear, construction workers need to use a variety of safety material at work. Such safety materials keep them safe at work. They include gloves, earplugs, face shields, safety glasses, helmets, and hard hats.

- Painters white workwear

Painters don’t have to deal with a lot of risks at work when compared to other professions. As a result, they are wearing pretty simple workwear. For example, a painter can either wear a long-sleeved shirt or a short-sleeved shirt. However, it is better if the shirt is made out of a breathable material. This is the main reason on why most painters prefer to use cotton.

It is pretty much the same for pants that painters wear as well. The pants need to be comfortable and relaxed. On the other hand, they need to be loose, which will help them to get their job done without any obstructions. For example, painters will need to climb on ladders quite often. The attire that painters wear should be in a position to help them get their job done without any challenges.

- Carpenters

It is also quite essential for the carpenters to pay extra attention towards the attire that they wear when trying to get the job done. That’s because carpenters have to deal with the risk associated with flying debris throughout the day at their work. On top of that, they will have to deal with the risk associated with heavy noise as well. Therefore, carpenters who don’t wear appropriate workwear will have a higher possibility of getting into injuries in the long run.

The hi vis workwear that carpenters wear need to be properly fitting. Moreover, they need to be comfortable as well. it is better if the carpenters can wear long pants as well as long-sleeved shirts. Moreover, they can wear steel-toed boots, which provide utmost protection to their feet.

No matter what, it is quite important for the attire of carpenters to be quite comfortable and relaxed. However, they should not be too relaxed, as there is a higher possibility of getting them caught up in power tools while trying to get the job done.

To minimize the risk of running into injuries, carpenters will need to wear some safety equipment as well. For example, earmuffs can help carpenters to keep their ears protected. Likewise, safety glasses provide protection to the eyes. Face masks and respirators provide protection against flying debris. On top of all these, it is a great idea to wear a full face shield as well.

Final words

Now you have a clear idea about the different types of hi vis workwear that people who focus on different professions have to use. Then it is possible to get the job done, while staying away from injuries. If you work for any of these professions, you need to wear right hi vis workwear bought from the best suppliers out there.

Despite over 50 years of research in the field of Synthetic Materials, native Vein and Artery segments are most commonly used for Revascularization procedures in Cardiac Surgery. Unfortunately suitable Veins or Arteries are not always available for peripheral or Coronary Revascularization, on the other hand artificial grafts do not grow with the body and frequent replacement is must. More over artificial grafts are susceptible to infection, poor durability and calcification when being attacked by the immune system. But the development of functional Tissue Engineered Vascular Grafts (TEVG) using tissue engineering techniques and engineering principles has the potential of tremendously effecting Coronary and Peripheral Artery Bypass Surgeries.

During initial days of TEVG development, researchers were using vascular mixed cells for grafting. However, the cost and manpower for harvesting and culturing the cells was too burdensome. To overcome such problem Dr. Toshiharu Shinoka and Dr. Christopher Breuer of Yale New Haven Hospital have developed a novel therapy for Coronary Revascularization. They have utilized an innovative, highly efficient method for creating TEVGs. They took a biodegradable synthetic Scaffold, made of the same material as absorbable sutures and seeded the individual’s own cells onto it. The scaffold degrades by hydrolysis, ultimately leaving only the living vessel generated from seeded cells in the patient. The unique scaffold material is vital to the process because it is able to degrade in everyone and offers little variability. [1]

The construction of TEVG starts with harvesting the cells for grafting by bone marrow aspirate, where a needle is put through the cortex of the Spinal Bone and Marrow. The Marrow is drawn up and separated by density centrifugation. This yields Bone Marrow dry mononuclear cells that are directly seeded onto the scaffold by pipetting. Scaffold used are composed of polyglycolic acid and epsilon-caprolactone/L-Lactide. The seeded scaffolds are then incubated in the patient’s plasma for two hours in order to attach cells to the scaffold [2]. The graft is now ready for implantation.

After implanting TEVGs in lambs, Dr. Breuer and Dr. Shinoka found that their grafts were functional, actually growing in size and remodeling themselves as valves in the host. But the surprising result was that seeded stem cells were no longer the part of neovessels but are replaced by host cells mainly endothelial cells and Smooth Muscle cells. Thus, TEVG vessel formation was governed by a paracrine effect, where the seeded cells send a message causing a cascade of events, ultimately resulting in a blood vessel free of any artificial matter.

The mechanism of vascular regeneration lies in triggering inflammatory mechanism by secreting monocyte chemoattractant proteins by seeded cells, which results in monocyte invasion. This invasion results in recruitment of host monocytes on scaffold. Then recruited host cells release a different series of cytokines, such as VEGF and PDGF, which further recruit actual cells that compose the blood vessel. Simultaneous to cell recruitment and tissue formation, the scaffold degrades so that only a blood vessel remains.

Implanting TEVGs in animals have shown promising results, but the only problem encountered is graft stenosis or constricting, which can be easily treated by an Angioplasty. Application of TEVG in Congenital Heart Surgery is promising and many laboratory researches are ongoing in this direction. Yale New Haven Hospital and Yale University School of Medicine are involved in Pilot scale study for clinical use of TEVG in Congenital Heart Surgery. This study is under Phase I clinical trial from 2008. [3] Looking forward TEVGs can be applied to the whole vascular system including arterial venous graft for Dialysis.

In fact, it’s hard to find a space in the home that doesn’t have at least one electronic device plugged in and turned on, but the question is, is all of this screen time good for your health? The answer might not be as obvious as you think.

The problem with screen time is never the technology itself; rather, it has more to do with how we choose to use our devices and whether or not they’re interfering with other aspects of life like sleep or exercise habits. As an example, watching TV before bed may cause trouble falling asleep because screens emit blue light which alters circadian rhythms (the internal clock) and suppresses melatonin levels which can contribute to insomnia if done close to bedtime.

What are the various health implications of excessive use of electronic gadgets?

Screen time has become an integral part of our lives with the constant use of electronic gadgets like smartphones, laptops, desktops, etc. There are many factors that need to be considered when it comes to screen time but one thing is for sure, too much of anything is bad! It’s important how we choose to use our devices and whether or not they’re interfering with other aspects of life like sleep or exercise habits.

How does screen time affect your sleep cycle?

Screen time can adversely affect your sleep cycle in a number of ways. There is significant evidence to suggest that screen time before bed can severely affect the quality and duration of sleep. One experiment showed a reduction in total sleep time, deep slow-wave sleep (SWS), and REM after viewing an hour’s worth of bright light from TV compared with dim light exposure. In addition, experts have reported seeing people who are using electronic devices late at night complain about insomnia for various reasons. As an example, blue LED emitted by these screens might be stimulating parts of our brains involved with alertness even when we aren’t looking directly at them or focusing on them.

The body temperature also increases while watching television, especially LCD TVs since they emit more heat than other types of TVs, and this too can affect sleep quality.

Teenagers and children are the highest at-risk group to get affected by electronic gadget overuse because of their lifestyle and habits. Watching TV before bedtime can also cause delayed circadian rhythms in teens which make them sleepy very late, for example past 11 pm or midnight.

It has been found that exposure to bright light from using electronic gadgets, for example, laptops or mobile phones after sunset can suppress melatonin secretion resulting in trouble falling asleep. People who use these devices while lying down might be putting themselves more at risk since this position could aggravate reflux disease (heartburn) where acid flows up into the oesophagus causing pain. Another harmful effect is related to blue LEDs used on all kinds of screens including mobile phones, tabs, and computers. These blue light LEDs have been found to be a potential health hazard for retina cells and might increase the risk of age-related macular degeneration, one kind of eye disease where central vision becomes gradually damaged. Furthermore, excessive use of electronic gadgets can cause physical injuries since people tend to hold them in an awkward position while texting or playing games on mobile devices.

The effects of reducing screen time:

Reducing screen time is an essential step towards healthy living. You can follow some tips which are given below to reduce your screen time and keep yourself safe from the harmful effects of excessive use of electronic gadgets:

Switch off all the electronic devices at least one hour before going to bed since they might interfere with sleep patterns.
Use same-day disposable lenses instead of conventional glasses as it reduces eye strain significantly.
If you feel discomfort or any pain while using an electronic device, stop using it immediately until you consult a doctor.
Take regular breaks during prolonged usage of screens so that eyes remain fresh for longer periods.

As you can see, there are several harmful effects related to excessive use of electronic gadgets which could affect our mental and physical well-being. Thus, even though you may be tempted by all the electronic items for sale, it is important that we should limit their usage at a particular time to avoid any negative impact on health.